Endocrine Abstracts

Experimental and clinical studies suggest that blocking the effects of angiotensin II increases insulin sensitivity, skeletal muscle glucose transport, and pancreatic blood flow which may contribute to the prevention of diabetes mellitus. Although large scale studies and meta-analysis reveal that the new onset of diabetes could be significantly decreased by ARBs in both hypertensive and normotensive patients, their effect on glucose regulation in patients already diagnosed wit...

Large scale clinical studies and meta-analysis suggest that treatment with angiotensin receptor blockers (ARBs) and angiotensin converting enzyme inhibitors (ACEIs) could have protective effect against diabetes development. While diuretics and β-blockers have some well known adverse effect on glycaemic regulation, ARBs/ACEIs’ effect on glucose regulation in patients already diagnosed with diabetes has not been investigated well enough. Also to the best of our knowled...

Periodontal disease frequency was screened and compared in 15 acromegalic patients with age and sex matched 50 healthy subjects. Periodontal evaluation included panographic radiography, plaque and gingival index and depth determination and clinical parameters. Estimated disease duration was 2–10 years in acromegalic patients (8 female, 7 male patients, 52±13 years). Five patients on somatostain analog therapy had inactive disease for at least 2 years and 10 patients ...

Aim: Hypocalcemia is a common problem after parathyroidectomy but is generally transient. In some cases the postoperative hypocalcemia is severe and prolonged despite normal or even elevated levels of parathyroid hormone (PTH). This phenomenon, called the hungry bone syndrome (HBS), occurs due to sudden withdrawal of PTH leading to a marked net increase in bone uptake of Ca, P, and Mg. We aimed to evaluate predictive factors for HBS development after parathyroidectomy.<p c...

Introduction: Indirect calorimetry is the most frequently used method to measure resting energy expenditure (REE), but the great expense of equipment precludes its widespread use. The best known REE calculation formula is the ‘Harris and Benedict Formula’. The aim of this study is to assess the impact of glucose metabolism status on REE.Methods: Data from 110 subjects with impaired glucose tolerance (IGT), 108 subjects with impaired fasting glu...

Aim: To determine whether multiple fine needle passes to the same thyroid nodule in the fine needle aspiration biopsy (FNA) session affect sufficient and/or atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) cytological result.Materials and Methods: Ultrasonography (US) and cyto-histopathology results of the nodules of patients who were diagnosed with thyroid nodules and underwent FNA between May-August 2021 wer...

Developments of the cancer immunology have increased the frequency of use of targeted therapies and immunomodulatory therapies. Although these treatments are effective on cancer cells, they also have toxicity on the thyroid gland. We aimed to evaluate the tyrosine kinase inhibitors(TKI) and immunotherapies-induced thyroid disorders, their relationship on disease prognosis and baseline serum thyroid stimulating hormone (TSH) levels effect on the development of thyroid dysfuncti...

Introduction: The aim of this study is to investigate association between Hashimoto’s thyroiditis (HT) and vestibular function and the possible effect of levothyroxine (LT4) treatment on vestibular functionPatients and methods: We recruited 61 patients with HT and 30 age and gender matched healthy individuals for the study. Of 30 patients with HT were on LT4 treatment (group I) and 31 patients were treatment naive (group II). None of the patients ha...

The prevalance of incidentally discovered adrenal masses increased in last three decades. The major clinical concern is the risk of malignancy and hormone overproduction but most of them are non-fonctional and benign. Current practices in the management of adrenal incidentalomas reevaluated the follow-up suggestions considering low probability of the transformation of a benign and non-functional adrenal mass to a malignant or functional one. Therefore, in the present study we ...

Introduction: Mucoceles-mucus containing benign cysts of paranasal sinuses- are common with an incidence of 1% but involvement of sphenoid sinus is much less common. In this case report, we reported a patient presented with hypopituitarism after sphenoid mucocele drainage operation.Case report: A 59- year-old woman was admitted to our endocrinology out-patient clinics with a complaint of fatigue over the past 2 months. One month prior to admission, she h...